A Closer Look at Our Patch Testing
- what-we-tested
CLERIVY’s Hydrocolloid Pimple Patch and Microdart Spot Patch were evaluated in six studies at Cutis Biomedical Research Center in Korea. Four studies followed daily use for one week; two assessed skin response after a single 24-hour patch application. Here is a closer look at the methods and findings for each product.
One Week of Daily Use
Hydrocolloid Pimple Patch
Two studies evaluated the Hydrocolloid Pimple Patch, used once daily for one week:
Sensitive-skin testing: CBRC-E-260610-52 included 23 participants with sensitive skin.
Non-comedogenic testing: CBRC-E-260610-53 included 22 participants with blemish-prone skin.
Microdart Spot Patch
Two studies evaluated the complete two-step routine: the Blemish Clearing Pad followed by the Microdart Spot Patch, used once daily for one week:
Sensitive-skin testing: CBRC-E-260611-54 included 23 participants with sensitive skin.
Non-comedogenic testing: CBRC-E-260611-55 included 21 participants with blemish-prone skin.
No assessed adverse skin reactions were observed in these four studies. The reports support sensitive-skin suitability and non-comedogenic tested status for the respective products. The Microdart findings apply to the pad-and-patch routine used in the studies.
Each study followed a single group for one week without a control group. The findings describe that period of use; they do not establish long-term results, and individual responses may vary.
Skin Response After a 24-Hour Patch Test
The Hydrocolloid Pimple Patch and Microdart Spot Patch were also tested separately in 31 adults each. A single patch was applied to the upper back for 24 hours. A researcher assessed the skin 1 hour and 24 hours after removal.
Hydrocolloid Pimple Patch: CBRC-I-260818-96-01; 31 participants.
Microdart Spot Patch: CBRC-I-260818-96-02; 31 participants.
No irritation reactions were observed at either assessment. Both reports recorded a mean skin reaction score of 0.00 and classified the products in the low-irritation category under the study criteria.
These tests excluded people with sensitive or hypersensitive skin. The 0.00 score describes the response observed in these participants during the test. It does not establish that a product is irritation-free, hypoallergenic, or suitable for every skin type.
Explore the 24-hour test method and the separate one-week study methods for more detail.
Explore the Results for Your Patch
Our Testing & Certifications page brings together the study summaries for both cosmetic patches. You can also explore the separate Hydrocolloid clinical results on its product page, or visit the Microdart Spot Patch testing section.
These studies concern the two cosmetic products named above. The Microdart Acne Patch is a separate OTC acne drug with 2% salicylic acid and its own Drug Facts.
Vegan and Cruelty-Free Status
Vegan certification and registration cover a different aspect of a product from skin testing. The Hydrocolloid Pimple Patch is certified by EVE VEGAN. The Microdart Spot Patch is registered with The Vegan Society. See the vegan and cruelty-free details for each product.
Related Reading
CLERIVY Product Testing & Certifications — study methods and results
Hydrocolloid vs Microdart — choose by spot stage
How to Use CLERIVY Patches — product-specific directions
Sources
Human-use reports CBRC-E-260610-52, CBRC-E-260610-53, CBRC-E-260611-54, and CBRC-E-260611-55; primary skin irritation reports CBRC-I-260818-96-01 and CBRC-I-260818-96-02; Cutis Biomedical Research Center, August 2026
CLERIVY Hydrocolloid Pimple Patch and Microdart Spot Patch are cosmetic products. They are not intended to treat, prevent, or cure acne or any other medical condition.
Last updated: September 6, 2026
